Psoriasis - Sample Essay

Psoriasis is a disorder of the skin which is chronic and it is associated with development of red scales on the skin surface which are covered by a flaky surface which is silvery. The disease is caused by activities that occur on the epidermis that is the first five layers that form the topmost part of the skin.

Development of this disease according to (Fortune 2000), starts at the bottom layer of the epidermis where the process of forming keratinocytes takes place. Keratinocytes are defined as cells of the hair which are immature and produce keratin a protein tough enough to form nails, hair and skin. In normal cases, keratinocytes grow at the bottom layer of the skin and then move to other layers. After getting to the top layers, they are shed and the process is not noticed. In people with psoriasis, the case is seen to be very different as the keratinocytes are formed rapidly and within four days they have already travelled from the basal layer to the top layer. They can therefore not be shed and end up piling up to form the plaques. The dermis is the underlying layer which contains blood, nerves and lymphatic system becomes swollen and red.

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According to (Dr. Nicole 2000) patients with psoriasis disease also have issues with their nervous systems. The major reason for this is because most of them get so concerned about their skin and an unhealthy status which leaves them in so much worry so that even some become so angry easily.

Doctor Nicole Ward also explains that, the spread of this disease could be facilitated by the nervous system. She explains that it facilitates the spread of plaque symmetrically on the skin and the increased number of neural fibers as well as their neuropeptides in psoriatic skin accelerates the rate of spread of the disease. Interactions with immunomodulatory networks by maybe the reflective of the nerve associated with peripheral sensory could also be a facilitating factor of the advancement and spread of this disease. Dr. Nicole concludes by saying that the most affected part of the nervous system is the psychology of a patient and with such stress about their risky life; the disease continues thriving in them.

The integumentary system is comprised of parts that protect the body from damages caused by the external surrounding for example abrasion and loss of water. These parts include the skin as well as its appendages. Psoriasis (Lanigan, 1991) affects the skin and thus the body is not protected from external harm. It hence becomes a risk to the patient sine activities such as excretion, regulation of body temperatures and detecting pain, temperatures and pressure do not take place as supposed. This is a big problem as it may lead to more serious diseases.

Patients with pustular psoriasis are said to experience muscle pains which are diffuse. This is mainly caused by reduced rates of metabolism in which case a patient is said to have a block in glycolysis. Doctors have also concluded that weaknesses of the skeletal muscle, is associated with psoriasis. This poses a great risk to these patients since their bodies normal functioning is hindered. Having a poor metabolic system weakens the body more and with a weak body, a patient could be in danger of contracting very many diseases in addition to psoriasis.

Psoriasis is a disease that affects almost all the body systems though some are greatly affected than others. Since its cause is not yet discovered, it also means that its cure has not also been fully established and this thus makes it a dangerous disease that people should be very quick to report any symptom that is associated with it for preventive measures to be taken.


  • Farber, E.M., Rein, G., and Lanigan, S.W. (1991). Stress and Psoriasis. International Journal of Dermatology. 30(1): 8-12.
  • Fortune, D.G., Richards, H.L., Main, C.J., and Griffiths, C.E.M. (2000). Pathological worrying, illness perceptions and disease severity in patients with psoriasis. British Journal of Health Psychology. 5(1): 71-82.
  • Fortune, D.G., Richards, H.L., Main, C.J., and Griffiths, C.E.M. (2000). Pathological worrying, illness perceptions and disease severity in patients with psoriasis. British Journal of Health Psychology. 5(1): 71-82.


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